The efficacy of local anaesthetic for pain after iliac bone harvesting: A randomised controlled trial
| Autor: | Linda Adamson, Paul Coulthard, Debbie Jackson-Leech, Helen V Worthington, Kousar Ali Khan Afridi, Richard Oliver |
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| Jazyk: | angličtina |
| Předmět: |
Reconstructive surgery
medicine.medical_specialty Evening Limp Placebo Iliac crest Transplantation Autologous law.invention Ilium Postoperative pain Randomized controlled trial law medicine Humans Anesthetics Local Levobupivacaine Mobility Pain Postoperative Bone Transplantation Randomised control trial business.industry General Medicine Length of Stay Bupivacaine Surgery Transplantation medicine.anatomical_structure Anesthesia Tissue and Organ Harvesting medicine.symptom Morbidity business Levobupivicaine medicine.drug Local anaesthetic |
| Zdroj: | International Journal of Surgery. (1):57-63 |
| ISSN: | 1743-9191 |
| DOI: | 10.1016/j.ijsu.2007.07.002 |
| Popis: | IntroductionAutogenous bone grafting is commonly used in reconstructive surgery but postoperative pain from the donor site can be severe, delaying early mobilisation and preventing discharge from hospital.MethodAn RCT of levobupivacaine infusion (16.25mg/h for 24h) of iliac crest wounds versus placebo. Postoperative pain was recorded immediately on returning to the ward, then at 1, 2, 3, 4, 5, 6h, morning and evening on subsequent days until discharge, and at the 7-day clinic appointment. Mobility was recorded twice daily and at 7days.ResultsOf 46 evaluable patients, 25 were randomised to levobupivacaine and 21 to placebo. Mean pain scores for (i) average pain from initial assessment to 6h; (ii) 1day in the morning; (iii) 1day in the evening; (iv) at 2days; and (v) follow-up were all statistically significant in favour of lower pain scores in the levobupivicaine group (p-values all |
| Databáze: | OpenAIRE |
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