Missed opportunities for diagnosing viral hepatitis C in Poland. Results from routine HCV testing at the Emergency Department in the Hospital for Infectious Diseases in Warsaw
| Autor: | Andrzej Horban, Maksymilian Bielecki, Justyna D. Kowalska, Karolina Pyziak-Kowalska |
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| Rok vydání: | 2019 |
| Předmět: |
education.field_of_study
medicine.medical_specialty Original Paper Blood transfusion Hepatology business.industry medicine.medical_treatment Public health Population prevalence Emergency department medicine.disease Liver disease rapid test Internal medicine HCV medicine Seroprevalence risk factors Poland Prospective cohort study education business Viral hepatitis |
| Zdroj: | Clinical and Experimental Hepatology |
| ISSN: | 2392-1099 |
| Popis: | Aim of the study Current statistics indicate that approximately 150,000 (0.5%) people in Poland suffer from active hepatitis C virus (HCV) infection, but only 20% among them are aware of their status. This project is based on the concept that screening based on the presence of HCV-related risks (a patient's individual history and behavioural risk factors) is more effective than obligatory testing of the whole population. This study investigates prevalence of serological markers for HCV among patients with a risk of exposure to HCV infection. Material and methods The prospective study concerning patients of 18 years and older was conducted at the Emergency Department (ED) of the Hospital for Infectious Diseases in Warsaw (from 15 September 2016 until 23 July 2018). The inclusion criteria were: a blood transfusion before 1992, more than three hospitalizations in the lifetime, suspected liver disease, elevated aminotransferase activity, imprisonment, patient's own initiative, history of injecting drug use. The rapid HCV test was performed on all patients who fulfilled inclusion criteria. The statistical analyses included calculating serological positivity rate and comparing risk-group characteristics. Results Among 1502 patients consulted at the emergency department with risk factors for HCV infection during the study period, the HCV test was performed in 1487 cases. New diagnoses were confirmed in 25 cases, HCV seroprevalence was 1.68%, all patients were linked to care, 21/25 (84.0%) were HCV RNA positive. Conclusions The study confirms that routine rapid testing in certain risk groups constitutes an essential tool for identifying new HCV infections and might have an important role for public health. |
| Databáze: | OpenAIRE |
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