Left ventricular hypertrophy and preclinical impaired glucose tolerance and diabetes mellitus contribute to abnormal left ventricular diastolic function in hypertensive patients
| Autor: | Abdul-Majeed Salmasi, Mark Dancy, Sara Rawlins |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Male medicine.medical_specialty Ambulatory blood pressure Isometric exercise Assessment and Diagnosis Left ventricular hypertrophy Diabetes Complications Impaired glucose tolerance Electrocardiography Ventricular Dysfunction Left chemistry.chemical_compound Internal medicine Diabetes mellitus Glucose Intolerance Diabetes Mellitus Internal Medicine medicine Humans Aged Aged 80 and over Advanced and Specialized Nursing Triglyceride business.industry Ultrasonography Doppler General Medicine Blood Pressure Monitoring Ambulatory Middle Aged medicine.disease Blood pressure chemistry Hypertension Cardiology Regression Analysis Female Hypertrophy Left Ventricular Cardiology and Cardiovascular Medicine business Body mass index |
| Zdroj: | Blood Pressure Monitoring. 10:231-238 |
| ISSN: | 1359-5237 |
| DOI: | 10.1097/01.mbp.0000172710.82287.36 |
| Popis: | Background Impaired left ventricular diastolic function is not uncommon in patients with either diabetes mellitus or hypertension. This study was carried out to assess the contribution of left ventricular hypertrophy, high blood pressure, preclinical impaired glucose tolerance and diabetes mellitus to left ventricular diastolic function in patients attending a hypertension clinic. Methods Echocardiography, 24-h ambulatory blood pressure monitoring and oral glucose tolerance tests were carried out in 152 consecutive hypertensive patients who had no evidence of ischaemic heart disease and were not known to be diabetic. From echocardiography, E/A (peak velocity of early/atrial filling waves of the transmitral flow) at rest and at peak standardized isometric exercise using handgrip, left ventricular mass index and deceleration time of the E wave were derived. Results Patients with impaired glucose tolerance and diabetes mellitus had lower E/A than the euglycaemic subjects both at rest (P= 0.0073) and during isometric exercise (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|