Temperature feedback-controlled photothermal treatment with diffusingapplicator: theoretical and experimental evaluations
| Autor: | Trung Hau Nguyen, Suhyun Park, Hyun Wook Kang, Kyu Kyu Hlaing |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Temperature monitoring
ocis:(140.6810) Thermal effects Thermal injury Computer science ocis:(000.4430) Numerical approximation and analysis PID controller Energy delivery Nanotechnology Irradiation time ocis:(230.1980) Diffusers Photothermal therapy 01 natural sciences Atomic and Molecular Physics and Optics Article Degree (temperature) 010309 optics 03 medical and health sciences ocis:(170.1610) Clinical applications 0302 clinical medicine Control theory 0103 physical sciences 030211 gastroenterology & hepatology Biotechnology Biomedical engineering |
| Zdroj: | BIOMEDICAL OPTICS EXPRESS(7): 5 Biomedical Optics Express |
| Popis: | To minimize thermal injury, the current study evaluated the real-time temperature monitoring with a proportional-integrative-derivative (PID) controller during 980-nm photothermal treatment with a radially-diffusing applicator. Both simulations and experiments demonstrated comparable thermal behaviors in temperature distribution and the degree of irreversible tissue denaturation. The PID-controlled application constantly maintained the pre-determined temperature of 353 K (steady-state error = < 1 K). Due to constant energy delivery, coagulation volumes linearly increased up to 1.04 +/- 0.02 cm(3) with irradiation time. Integration of temperature feedback with diffuser-assisted photothermal treatments can provide a feasible therapeutic modality to treat pancreatic tumors in an effective manner. (C) 2016 Optical Society of America |
| Databáze: | OpenAIRE |
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