Definition of two LD antigens in rhesus monkeys
| Autor: | Bruce A. Maurer, David F. Siwarski, John R. Neefe |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Male
LD Antigens Genotype Genetic Linkage Immunology Serum protein Locus (genetics) Biology Biochemistry law.invention Epitopes Antigen Gene Frequency law Histocompatibility Antigens Genetics Immunology and Allergy Animals Typing Lymphocytes Gene Recombination Genetic Histocompatibility Testing General Medicine Haplorhini Virology Macaca mulatta Recombinant DNA Properdin Macaca Female Lymphocyte Culture Test Mixed Complement Factor B |
| Zdroj: | Tissue antigens. 13(2) |
| ISSN: | 0001-2815 |
| Popis: | Two rhesus (Macaca mulatta) monkey lymphocyte-defined (LD) antigens have been identified using two typing cells as stiumlators in a one-way mixed leukocyte culture (MLC) assay. An analysis of the genetic behavior of these LD antigens in six rhesus monkey families revealed that both antigens were linked with RhLA. One probable recombinant indicated that the LD locus lies outside the two known RhLA-SD loci and the locus which controls the serum protein, properdin B(Bf). These two antigens, LD1 and LD2, had observed gene frequencies of 0.07 and 0.25, respectively. Neither of these two new LD antigens was significantly associated with any serologically defined (SD) antigen. |
| Databáze: | OpenAIRE |
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