A rare cause of hypoglycemia in a type 2 diabetic patient: insulinoma

Autor: Soner Cander, Ozlem Saraydaroglu, Nalan Yildirim, Ozen Oz Gul, Oguz Kaan Unal, Sazi Imamoglu
Přispěvatelé: Uludağ Üniversitesi/Tıp Fakültesi/Endokrinoloji ve Metabolizma Anabilim Dalı., Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı., Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı., Cander, Soner, Gül, Özen Öz, Yıldırım, Nalan, Ünal, Oğuz Kaan, Saraydaroğlu, Özlem, İmamoğlu, Şazi, AAH-9701-2021, AAI-1005-2021
Rok vydání: 2012
Předmět:
Sulfonylurea compounds
Pediatrics
Hydrocortisone
endocrine system diseases
Endocrinology
Diabetes and Metabolism
Glucose blood level
Antidiabetic agent
Type 2 diabetes
Spontaneous hypoglycemia
Hyperinsulinemia
Endocrinology
Hypoglycemic agents
Sulfonylurea
Pancreas surgery
Insulin
Treatment outcome
Insulinoma
Hypoglycemia
Multiple Endocrine Neoplasia Type 1
Endocrinology & metabolism
Priority journal
Tumor
Hospitalization
Diabetic patient
Causes of hypoglycemia
Insulin blood level
Drug dose reduction
Female
Human
medicine.medical_specialty
Pancreatic neoplasms
Recurrent hypoglycemia
Histopathology
Article
Cinnarizine
Disorientation
Hyperinsulinism
Diabetes mellitus
Type 2 diabetes mellitus
Case report
Computer assisted tomography
Postoperative period
Internal Medicine
medicine
Humans
Clinical evaluation
Aged
business.industry
nutritional and metabolic diseases
Type 2 Diabetes Mellitus
Diabetes mellitus
type 2
Follow up
medicine.disease
Surgery
Glucose
Thiamine derivative
Carvedilol
Hydrocortisone blood level
Amlodipine
Echography
Non insulin dependent diabetes mellitus
business
C peptide
Zdroj: Journal of Diabetes and its Complications. 26:65-67
ISSN: 1056-8727
DOI: 10.1016/j.jdiacomp.2011.12.003
Popis: Recurrent episodes of hypoglycemia in patients with diabetes are often associated with the ongoing treatment regimen. However, despite changes in treatment modalities, assessment of the causes of hypoglycemia in nondiabetic patients in the presence of severe and recurrent hypoglycemia is very important. The treatment that had been provided for 6 years in a 67-year-old female patient with type 2 diabetes mellitus was discontinued due to hypoglycemic episodes that presented for the previous 2 years. The patient experienced persistent hypoglycemia after cessation of the treatment and was hospitalized for further examination. Spontaneous hypoglycemia with a final diagnosis of insulinoma was established following histopathologic evaluation and was relieved postoperation. Insulinoma is rarely encountered as a cause of hypoglycemia in patients with type 2 diabetes. Insulin-secreting tumors should be considered where hypoglycemic episodes occur despite discontinuation of insulin and other antidiabetic treatment with endogenous hyperinsulinemia being noncompliant with the blood glycemic levels.
Databáze: OpenAIRE
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