Characterization of cerebrospinal fluid monoamine metabolites in peripubertal chimpanzees (Pan troglodytes)

Autor: M.W. Musso, M.B. Fontenot, G. M. Anderson, Sheree L. Watson
Rok vydání: 2009
Předmět:
Zdroj: Journal of medical primatology. 39(1)
ISSN: 1600-0684
Popis: Background Assessment of cerebrospinal (CSF) monoamine metabolites 5-hydroxyindoeacetic acid (5-HIAA) and homovanillic acid (HVA), and the serotonin precursor tryptophan (TRP), in chimpanzees may help in understanding the neurobiology underlying aggressive, impulsive behavior in humans and non-human primates. Methods Two CSF samples were obtained from 11 peripubertal chimpanzees 8 months apart and were assayed for monoamine metabolite and TRP concentrations. Results Substantial inter-individual stability was observed for 5-HIAA (n = 11; r = 0.83, P
Databáze: OpenAIRE