Early Detection of Chronic Obstructive Pulmonary Disease Using Radionuclide Lung-Imaging Procedures
| Autor: | Barry Calvarese, Roger Detels, Anne H. Coulson, Donald P. Tashkin, Dennis Elam, Stanley N. Rokaw, Sawtantra K. Chopra, Osvaldo E. Anselmi, George V. Taplin |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine Pulmonary Circulation medicine.medical_specialty Time Factors Adolescent Physical examination Critical Care and Intensive Care Medicine Indium Pulmonary function testing medicine Humans Lung Diseases Obstructive Respiratory system Radionuclide Imaging Screening procedures Aged Inhalation medicine.diagnostic_test business.industry Respiratory disease Technetium Forced Expiratory Flow Rates Middle Aged respiratory system medicine.disease Nitrogen washout Evaluation Studies as Topic Spirometry Chronic Disease Female Radiology Lung Volume Measurements Cardiology and Cardiovascular Medicine business Perfusion Xenon Radioisotopes |
| Zdroj: | Chest. 71:567-575 |
| ISSN: | 0012-3692 |
| DOI: | 10.1378/chest.71.5.567 |
| Popis: | One hundred subjects answered a respiratory questionnaire and underwent a physical examination, tests of pulmonary function, and three radionuclide lung-imaging procedures. The results of the radionuclide procedures were compared with each other and with pulmonary function tests and other diagnostic findings to determine their relative sensitivity for detecting evidence of early obstructive airway disease. Perfusion lung imaging was less sensitive than most of the other diagnostic tests evaluated. The aerosol and xenon lung-imaging procedures revealed abnormalities with approximately the same frequency as each other, but more often than any one group of pulmonary function tests, including spirometric data, maximal expiratory flow-volume curves, alveolar-arterial oxygen gradient, or indices derived from single-breath nitrogen washout. We concluded that xenon and aerosol lung-imaging studies are sensitive and useful screening procedures for detecting evidence of early localized obstructive airway disease and for locating regional abnormalities in the airways of patients with respiratory disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|