Macrophagic myofasciitis-associated dysfunctioning: An update of neuropsychological and neuroimaging features
| Autor: | Romain K. Gherardi, François-Jérôme Authier, Sarah Souvannanorath, Paul Blanc-Durand, Paul Kauv, Emmanuel Itti, Marie Abrivard, Axel Van Der Gucht, Mehdi Aoun Sebaiti |
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| Přispěvatelé: | Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Excitabilité nerveuse et thérapeutique (ENT), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-EA 4391, Service de Physiologie Explorations Fonctionnelles-Hôpital Henri Mondor |
| Rok vydání: | 2018 |
| Předmět: |
030203 arthritis & rheumatology
Myositis business.industry [SDV]Life Sciences [q-bio] Cognitive disorder Macrophagic myofasciitis Neuropsychology Executive functions medicine.disease 3. Good health Functional imaging 03 medical and health sciences 0302 clinical medicine Rheumatology Neuroimaging Functional neuroimaging medicine Chronic fatigue syndrome Humans Fasciitis Cognition Disorders business Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Best Practice and Research: Clinical Rheumatology Best Practice and Research: Clinical Rheumatology, Elsevier, 2018, 32, pp.640-650. ⟨10.1016/j.berh.2019.04.003⟩ |
| ISSN: | 1521-6942 |
| Popis: | Macrophagic myofasciitis (MMF) syndrome is a subtype of autoimmune/inflammatory syndrome induced by adjuvants (ASIA) or Shoenfeld's syndrome, characterized by the presence of stereotyped inflammatory lesions at muscle biopsy attesting the long-term persistence of aluminum hydroxide particles at the site of previous immunization. Most frequently reported symptoms are chronic arthromyalgias and fatigue and cognitive complaint. MMF-associated cognitive disorder (MACD) is characterized by the dysfunctioning of attention, executive functions, short-term term and long-term memory, and, in some instances, left ear extinction. MACD is expressed in a chronic, nonevolving, well-defined syndromic framework within which the expression in terms of severity differs from one patient to another. While brain MRI is usually noncontributive, functional imaging using SPECT and PET has revealed the existence of a suggestive pathological pattern with involvement of posterior associative areas, temporal lobes, limbic system, and cerebellum. Put together, neuropsychological and functional neuroimaging investigations support the view that MACD relates to organic central nervous system involvement. |
| Databáze: | OpenAIRE |
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