Mediterranean Diet Reduces Risk of Incident Stroke in a Population With Varying Cardiovascular Disease Risk Profiles
| Autor: | L. K. M. Bain, Amy Jennings, Katherine E. Paterson, Phyo K. Myint, Ailsa A Welch, Marleen A. H. Lentjes, Kay-Tee Khaw |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Mediterranean diet Original Contributions Clinical Sciences Population MEDLINE Stroke risk 03 medical and health sciences 0302 clinical medicine cardiovascular disease Internal medicine Epidemiology Medicine 030212 general & internal medicine education Stroke 2. Zero hunger Advanced and Specialized Nursing education.field_of_study business.industry medicine.disease stroke 3. Good health ComputingMethodologies_DOCUMENTANDTEXTPROCESSING Disease risk epidemiology women Neurology (clinical) diet Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery Cohort study |
| Zdroj: | Stroke |
| ISSN: | 1524-4628 0039-2499 |
| Popis: | Supplemental Digital Content is available in the text. Background and Purpose— Although some evidence has found that the Mediterranean diet (MD) is protective for stroke risk, few studies have investigated whether this relationship differs by sex or cardiovascular disease risk. Methods— We investigated the relationship between adherence to the MD score, estimated using 7-day dietary diaries and risk of incident stroke in an observational prospective population-based cohort study of 23 232 men and women (54.5% women) aged 40 to 77 years who participated in the European Prospective Investigation into Cancer study in Norfolk, United Kingdom. Risk of incident stroke was calculated using multivariable Cox regression, in the whole population, and also stratified by sex and cardiovascular disease risk profile, using the Framingham risk score. Results— During 17.0 years of follow-up (395 048 total person-years), 2009 incident strokes occurred. Risk of stroke was significantly reduced with greater adherence to the MD score (quartile 4 versus quartile 1 hazard ratio [HR], 0.83; 95% CI, 0.74–0.94; P-trend |
| Databáze: | OpenAIRE |
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