Quality of life in patients with retinitis pigmentosa submitted to intravitreal use of bone marrow-derived stem cells (Reticell -clinical trial)
| Autor: | Rafael S. Arcieri, Rodrigo Jorge, Neiglene F Souza, Andre Messias, Lia C Martins, Milton A Ruiz, Rubens Camargo Siqueira, Katharina Messias |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Cell- and Tissue-Based Therapy Medicine (miscellaneous) Bone Marrow Cells Disease QUALIDADE DE VIDA Biochemistry Genetics and Molecular Biology (miscellaneous) Cell therapy Quality of life Surveys and Questionnaires Internal medicine Ophthalmology Retinitis pigmentosa medicine Humans In patient Vision Ocular business.industry Stem Cells Research Cell Biology medicine.disease Clinical trial medicine.anatomical_structure Quality of Life Molecular Medicine Bone marrow Stem cell business Retinitis Pigmentosa Stem Cell Transplantation |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP Stem Cell Research & Therapy |
| Popis: | Introduction Retinitis pigmentosa (RP) is a severe neurodegenerative disease of the retina that can lead to blindness. Even without treatment, a clinical study with the use of stem cells is currently underway and the results are being evaluated. In the present report we assess the vision-related quality of life in patients with RP submitted to intravitreal use of bone marrow-derived stem cells. Method The study included 20 patients with RP submitted to intravitreal use of bone marrow-derived stem cells. We evaluate the vision-related quality of life (VRQOL) of patients using the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25). Patients were scheduled to answer the questionnaire before treatment and 3 and 12 months after treatment. Results All patients completed the survey as scheduled. There was a statistically significant improvement (P |
| Databáze: | OpenAIRE |
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