Sialic Acid Level in Maternal and Neonatal Lymphocytes and Sera Correlated to Birth Order and Sex of the Neonate
| Autor: | J. Notmann, H. Levinsky, F. Dulitzky, Luise Komlos, I. Halbrecht, Jacob Hart, S. Kyzer, J. Landmann |
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| Rok vydání: | 1992 |
| Předmět: |
Male
Lymphocyte Biology Andrology chemistry.chemical_compound Reference Values medicine Humans Lymphocytes Sex Characteristics Infant Newborn N-Acetylneuraminic Acid Peripheral blood Sialic acid Birth order medicine.anatomical_structure chemistry Recien nacido Pediatrics Perinatology and Child Health Correlation analysis Immunology Sialic Acids Female Birth Order Parity (mathematics) Developmental Biology |
| Zdroj: | Neonatology. 62:379-384 |
| ISSN: | 1661-7819 1661-7800 |
| DOI: | 10.1159/000243895 |
| Popis: | Sialic acid (N-acetylneuraminic acid) was determined 1 h after normal term deliveries on peripheral blood lymphocytes from 42 mother-neonate pairs and in 29 maternal and neonatal sera. Results were evaluated according to maternal parity and sex of the neonate. The cases were divided into two groups: primiparae, and secundi- and multiparae. In primiparae the sialic acid level on lymphocytes from male neonates and from their mothers was by 23–30% decreased as compared to female neonatal and maternal cells. In the higher parity group, a significantly increased sialic acid level was found on lymphocytes from male as compared to female neonates, and maternal serum sialic acid concentration, unrelated to the newborns’ sex, was by 17–20% increased as compared to primiparae. The results suggest that with increasing parity higher levels of sialic acid on male neonatal cells may possibly contribute to mask fetal male-specific histocompatibility antigens. Increased sialic acid levels in maternal sera from secundi- and multiparae suggest its possible contribution to an increased serum blocking effect. |
| Databáze: | OpenAIRE |
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