Autor: |
Joseph Zenga, Musaddiq J. Awan, Anne Frei, Ellie Petrie, Guru Prasad Sharma, Aditya Shreenivas, Monica Shukla, Heather A. Himburg |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Head Neck |
Popis: |
BACKGROUND: Despite the importance of immune response and environmental stress on head and neck cancer (HNC) outcomes, no current pre-clinical stress model includes a humanized immune system. METHODS: We investigated the effects of chronic stress induced by social isolation on tumor growth and human immune response in subcutaneous HNC tumors grown in NSG-SGM3 mice engrafted with a human immune system. RESULTS: Tumor growth (p |
Databáze: |
OpenAIRE |
Externí odkaz: |
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