The Effects of Short-Term Lens Wear and Eye Rubbing on the Corneal Epithelium

Autor: Gregory Kalogeropoulos, Isabelle Jalbert, Shaun Chang, Thomas Bolton
Rok vydání: 2009
Předmět:
Zdroj: Eye & Contact Lens: Science & Clinical Practice. 35:255-259
ISSN: 1542-2321
DOI: 10.1097/icl.0b013e3181b4ec39
Popis: Objectives To measure the effects of short-term high oxygen-transmissible (Dk) soft and rigid contact lens wear and eye rubbing on basal epithelial appearance and epithelial thickness. Methods Ten subjects were enrolled in a randomized crossover study. The subjects' left eye was used as a control, and the right eye either wore a high Dk soft lens, high Dk parallel fitted rigid gas-permeable lens, or was rubbed on 3 separate days. Epithelial basal cell regularity and central and peripheral epithelial thickness were assessed before and after 6-hr soft or rigid lens wear or 10-min rubbing using in vivo confocal microscopy and modified optical pachometry. Results Basal cell regularity was unaffected by short-term lens wear or eye rubbing (Friedman Test, P=0.11 and 0.37 in test and control eyes, respectively). The peripheral epithelium was thicker than the central epithelium (repeated-measures analysis of variance, P=0.03) but remained unaffected by short-term lens wear or eye rubbing (repeated-measures analysis of variance, P>0.05, power Conclusions Corneal epithelial thickness and basal cell morphology were not affected by short-term lens wear or eye rubbing in this pilot study.
Databáze: OpenAIRE