Bilateral Pupillary Involvement as a Clinical Presentation of Herpes Zoster Ophthalmicus
| Autor: | Yun Feng, Rupesh Agrawal, Yan Ma, Yuhe Tian, Xia Chen |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
genetic structures business.industry Abnormal pupillary light reflex eye diseases Pupil Constriction Ophthalmology Herpes Zoster Ophthalmicus Immunology and Allergy Medicine sense organs Pupillary light reflex Presentation (obstetrics) Pupilometer business Subclinical infection |
| Zdroj: | Ocular Immunology and Inflammation. 31:87-91 |
| ISSN: | 1744-5078 0927-3948 |
| DOI: | 10.1080/09273948.2021.1986075 |
| Popis: | Purpose: Herpes zoster ophthalmicus (HZO) is traditionally considered as an unilateral disease. However, subclinical involvements in the contralateral eye structures are evidence, giving rise to a broader understanding of varicella-zoster virus (VZV) infection. Methods: We enrolled 20 eyes of 10 patients with HZO and 12 eyes of healthy controls to investigate the bilateral features of HZO patients using a hand-held pupillometer and a Cochet-Bonnet esthesiometer. Results: Maximum pupil size before constriction (INT) and minimum diameter when pupil constricts at peak (END) were significantly smaller in patients affected eyes compared with those in controls (p < .05). Interestingly, INT and END were significantly reduced in contralateral eyes of 20 affected patients and also in comparison to control group (p < .001 and p = .034 respectively). Conclusion: The contralateral eyes may have subclinical involvement in patients with HZO based on significantly abnormal pupillary light reflex (PLR). Pupillometer provides a primary and convenient method to investigate the anatomy and pathology of the PLR. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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