Inhibitory Effect of 'Isocholesterol' on the Absorption of Cholesterol

Autor: Charles H. Duncan, Maurice M. Best, Joan D. Watheii
Rok vydání: 1957
Předmět:
Zdroj: Circulation Research. 5:401-404
ISSN: 1524-4571
0009-7330
DOI: 10.1161/01.res.5.4.401
Popis: The presence on carbon-3 of a free hyclroxyl group that may be esterified is a common characteristic of the known sterol inhibitors of cholesterol absorption. The 30-carbon sterols found in wool fat possess such a group, but differ from the previously demonstrated inhibitors of cholesterol absorption in that they do not form insoluble precipitates with digitonin. To determine whether these substances would influence cholesterol absorption, "isocholesterol," a mixture of 30-carbon wool fat sterols, has been fed to the albino rat alone and in combination with cholesterol.
Databáze: OpenAIRE
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