Deoxygenation of Unhindered Alcohols via Reductive Dealkylation of Derived Phosphate Esters
| Autor: | Sarwat Chowdhury, Robert F. Standaert |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Green chemistry
Lithium triethylborohydride 010405 organic chemistry fungi Organic Chemistry food and beverages Alcohol Primary alcohol Alkylation 010402 general chemistry 01 natural sciences 0104 chemical sciences chemistry.chemical_compound chemistry Organic chemistry Organic synthesis Deoxygenation Tetrahydrofuran |
| Zdroj: | The Journal of Organic Chemistry. 81:9957-9963 |
| ISSN: | 1520-6904 0022-3263 |
| Popis: | Primary alcohols can be deoxygenated cleanly and in yields of 60-95% by reduction of derived diphenyl phosphate esters with lithium triethylborohydride in tetrahydrofuran at room temperature. Selective deoxygenation of a primary alcohol in the presence of a secondary alcohol was demonstrated. The two-step process can be performed in one pot, making it simple and convenient. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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