Clinical insights into a tertiary care center cohort of patients with bicuspid aortic valve

Autor: Anne-Sophie Simoni, Gilbert Habib, Gaëlle Odelin, Stéphane Zaffran, Gwenaëlle Collod-Béroud, Giulia Norscini, Jean-François Avierinos, Alexis Theron, Frederic Collart, Anissa Touil, Noémie Resseguier
Přispěvatelé: Gall, Valérie, Marseille medical genetics - Centre de génétique médicale de Marseille (MMG), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital de la Timone [CHU - APHM] (TIMONE), Aix Marseille Université (AMU)
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Adult
Male
medicine.medical_specialty
Younger age
Heart disease
Bicuspid aortic valve
[SDV]Life Sciences [q-bio]
Population
Heart Valve Diseases
Aortic regurgitation
Regurgitation (circulation)
Tertiary care
Tertiary Care Centers
Bicuspid Aortic Valve Disease
[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
Predictive Value of Tests
Internal medicine
medicine
Humans
Radiology
Nuclear Medicine and imaging
education
Aged
Retrospective Studies
education.field_of_study
[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology
business.industry
Aortic stenosis
Aortic Valve Stenosis
Middle Aged
medicine.disease
[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
[SDV] Life Sciences [q-bio]
Stenosis
Aortic Valve
Cohort
Cardiology
Cardiology and Cardiovascular Medicine
business
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Zdroj: International Journal of Cardiovascular Imaging
International Journal of Cardiovascular Imaging, Springer Verlag, 2021, 38 (1), pp.51-59. ⟨10.1007/s10554-021-02366-1⟩
International Journal of Cardiovascular Imaging, 2021, 38 (1), pp.51-59. ⟨10.1007/s10554-021-02366-1⟩
ISSN: 1569-5794
1573-0743
Popis: International audience; Although bicuspid aortic valve (BAV) is one of the most common congenital heart diseases, clinical data associated with valve dysfunction are still limited. We evaluated clinical characteristics and echocardiography of French patients with BAV associated with leaking and stenosis degeneration. We initiated a prospective registry from 2014 to 2018 at a tertiary center. A total of 223 patients (168 males [75%], age 53 ± 17 years) were enrolled. Among these patients 83% had left–right coronary cusps fusion, 80% Sievers type 1 BAV and 49% showed aortic dilatation. Twenty-four patients (11%) had normal valve function, 66 patients (31%) had aortic stenosis (AS), 91 patients (41%) had aortic regurgitation (AR) and 40 patients (17%) had AR and AS. BAV phenotype did not predict neither AS nor AR (all p > 0.1). By multivariable analysis, age > 50 (41.6[10.3–248.2], p
Databáze: OpenAIRE
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