Increasing the low residue diet to 3 days does not improve the bowel cleansing in hard to prepare patients: Post hoc analysis of a randomized controlled trial
| Autor: | Rosa Delgado, Anjara Hernández, Antonio J. Lara, David Nicolás-Pérez, Manuel Hernández-Guerra, Onofre Alarcón-Fernández, Enrique Quintero, Inmaculada Alonso, Alejandro Jiménez, Raquel de la Barreda-Heuser, Isabel Mascareño, Carla Amaral, Domingo Hernández, Vanessa Felipe, Goretti Hernández, Rafael Romero, Zaida Adrian, Antonio Z. Gimeno-García, Cristina Reygosa, Jose Luis Baute, Alberto Hernández, Yanira González |
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| Rok vydání: | 2020 |
| Předmět: |
Dietary Fiber
Male medicine.medical_specialty Time Factors Ascorbic Acid law.invention Polyethylene Glycols 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Internal medicine Post-hoc analysis medicine Humans Bowel cleansing In patient Single-Blind Method Prospective Studies Aged Hepatology business.industry Cathartics Gastroenterology Odds ratio Colonoscopy Middle Aged Ascorbic acid Diet 030220 oncology & carcinogenesis Preoperative Period Low residue diet Patient Compliance 030211 gastroenterology & hepatology Female Detection rate business |
| Zdroj: | Gastroenterologia y hepatologia. 44(3) |
| ISSN: | 0210-5705 |
| Popis: | Background Recent evidence suggests that the number of low residue diet (LRD) days does not influence the bowel cleansing quality in non-selected patients. However, there are not data in the subgroup of patients with risk factors of inadequate bowel cleansing. Objective The aim of this study was to assess whether a 3-day LRD improved the bowel cleansing quality in patients with risk factors of poor bowel cleansing. Patients and methods Post hoc analysis of a randomized controlled trial carried out between December 2017 and March 2018 in a tertiary care hospital. Patients with high risk of poor bowel cleansing were selected following a validated score. The patients were randomized to the 1-day LRD or 3-day LRD groups. All patients received a 2-L split-dose of polyethylene glycol plus ascorbic acid. Intention-to-treat (ITT) and per-protocol (PP) analyses were conducted for the main outcome. Results 135 patients (1-day LRD group = 67, 3-day LRD = 68) were included. The rate of adequate cleansing quality was not significantly different between the groups in the ITT analysis: 76.1%, 95% CI: [64.6–84.8] vs. 79.4%, 95% CI: [68.2–87.4]; odds ratio (OR) 1.2, 95% CI [0.54–2.73]) or in the PP analysis: 77.3%, 95% CI: [65.7–85.8] vs. 80.3%, 95% CI: [69.0–88.3]; OR 1.2, 95% CI [0.52–2.77]). Compliance with the diet or cleansing solution, satisfaction or difficulties with the LRD and the polyp/adenoma detection rates were not significantly different. Conclusion Our results suggest that 1-day LRD is not inferior to 3-day LRD in patients with risk factors of inadequate bowel cleansing. |
| Databáze: | OpenAIRE |
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