Bench-to-bedside review: Challenges of diagnosis, care and prevention of central catheter-related bloodstream infections in children
| Autor: | Walter Zingg, Volker Classen, Arash Afshari, Susanne Janum |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Catheterization
Central Venous/adverse effects Catheterization Central Venous medicine.medical_specialty Central catheter MEDLINE Vascular access Review Critical Care and Intensive Care Medicine Anti-Infective Agents/administration & dosage Catheters Indwelling Anti-Infective Agents Medicine Effective treatment Humans Intensive care medicine Child Cross Infection/diagnosis/prevention & control/therapy Cross Infection Catheter insertion ddc:617 business.industry Bench to bedside Catheter Catheters Indwelling/microbiology Catheter-Related Infections business Blood sampling Catheter-Related Infections/diagnosis/prevention & control/therapy |
| Zdroj: | Critical Care, Vol. 17, No 4 (2013) P. 238 Critical Care |
| ISSN: | 1364-8535 |
| Popis: | Central venous catheters (CVCs) are indispensable in modern pediatric medicine. CVCs provide secure vascular access, but are associated with a risk of severe complications, in particular bloodstream infection. We provide a review of the recent literature about the diagnostic and therapeutic challenges of catheter-related bloodstream infection (CRBSI) in children and its prevention. Variations in blood sampling and limitations in blood culturing interfere with accurate and timely diagnosis of CRBSI. Although novel molecular testing methods appear promising in overcoming some of the present diagnostic limitations of conventional blood sampling in children, they still need to solidly prove their accuracy and reliability in clinical practice. Standardized practices of catheter insertion and care remain the cornerstone of CRBSI prevention although their implementation in daily practice may be difficult. Technology such as CVC impregnation or catheter locking with antimicrobial substances has been shown less effective than anticipated. Despite encouraging results in CRBSI prevention among adults, the goal of zero infection in children is still not in range. More high-quality research is needed in the field of prevention, accurate and reliable diagnostic measures and effective treatment of CRBSI in children. |
| Databáze: | OpenAIRE |
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