Anti-Müllerian hormone and intersex states
| Autor: | Laurence Boussin, Claire Nihoul-Fékété, Nathalie Josso, Jean-Yves Picard, Bertrand Knebelmann |
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| Rok vydání: | 1991 |
| Předmět: |
Cloning
endocrine system medicine.medical_specialty Sexual differentiation biology urogenital system Endocrinology Diabetes and Metabolism Anti-Müllerian hormone medicine.disease Endocrinology Clinical research Internal medicine Fetal sex Male pseudohermaphroditism Persistent Müllerian duct syndrome biology.protein medicine Hormone |
| Zdroj: | Trends in endocrinology and metabolism: TEM. 2(6) |
| ISSN: | 1043-2760 |
| Popis: | Anti-Mullerian hormone (AMH), alias Mullerian-inhibiting substance or factor, plays a key role in fetal sex differentiation. The cloning of the human gene, a member of the transforming growth-factor-beta family and the development of immunochemical reagents recognizing circulating human AMH have opened new perspectives for clinical research. AMH assays and genetic studies now provide meaningful information regarding testicular function in infancy and the molecular basis of a rare form of male pseudohermaphroditism, the persistent Mullerian duct syndrome. |
| Databáze: | OpenAIRE |
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