Spatiotemporal Electrochemical Sensing in a Smart Contact Lens
Autor: | Herbert De Smet, Ian Underwood, Matthew Donora, Andres Vasquez Quintero |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Auxiliary electrode
Materials science Instrumentation 02 engineering and technology 010402 general chemistry 01 natural sciences Thermoplastic polyurethane Materials Chemistry Electrical and Electronic Engineering Thermoforming business.industry Metals and Alloys electrochemical sensing 021001 nanoscience & nanotechnology Condensed Matter Physics smart contact lenses 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials Contact lens Microelectrode Biosensors microelectrode arrays Optoelectronics non-invasive devices 0210 nano-technology business Biosensor Polyimide |
Zdroj: | Donora, M, Quintero, A V, de Smet, H & Underwood, I 2020, ' Spatiotemporal Electrochemical Sensing in a Smart Contact Lens ', Sensors and Actuators B: Chemical, vol. 303, 127203 . https://doi.org/10.1016/j.snb.2019.127203 |
DOI: | 10.1016/j.snb.2019.127203 |
Popis: | An electrochemical smart contact lens (ESCL) capable of real-speed spatiotemporal electrochemical sensing across the surface of the eye is demonstrated. Four microelectrode arrays, each comprising 33 gold microdiscs of 30 μm diameter, and a distributed common gold counter electrode, are integrated into a soft smart contact lens platform based on polyimide and thermoplastic polyurethane. Using a novel fast-switching chronoamperometric method, an electrochemical ‘video’ of concentration variation in a model eye under flow conditions is produced, in which the introduction, progress, mixing and drainage of fluid of varying concentration can be observed. The device builds on previous work towards a platform suitable for clinical use and has proven to be robust under expected use conditions, with sensing performance remaining unchanged after thermoforming and repeated mechanical deformation. This work represents a significant step forward in ESCL design, and constitutes significant progress towards a technology with real clinical utility. |
Databáze: | OpenAIRE |
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