Coagulation factors in chronic liver disease
| Autor: | G. W. K. Donaldson, Alexis Darg, S. H. Davies, John Richmond |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Chronic liver disease Gastroenterology Pathology and Forensic Medicine Thromboplastin Factor IX Liver disease Liver Function Tests Internal medicine Medicine Humans Aged Prothrombin time biology medicine.diagnostic_test business.industry Liver Diseases Factor V General Medicine Articles Blood Coagulation Disorders Factor VII Middle Aged medicine.disease Liver biopsy Chronic Disease biology.protein Prothrombin Time Female Prothrombin business Liver function tests medicine.drug |
| Zdroj: | Journal of clinical pathology. 22(2) |
| ISSN: | 0021-9746 |
| Popis: | Coagulation studies were carried out on 30 patients with chronic liver disease. The clotting defect was complex and involved factors V, VII, IX (Christmas factor), and prothrombin. Some patients showed a significant depression of factor IX in the presence of a normal one-stage prothrombin time. Thrombotest was found to be a good indicator of factor IX deficiency in this group of patients and may be of use as an additional liver function test. The screening of patients with liver disease for surgery or liver biopsy should assess the coagulation factors involved in both intrinsic and extrinsic thromboplastin generation. |
| Databáze: | OpenAIRE |
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