Immobilization of wild giant panda (Ailuropoda melanoleuca) with dexmedetomidine-tiletamine-zolazepam
| Autor: | Yipeng Jin, Tianchun Pu, Degui Lin, Xiaobin Liu, Hongqian Xu, Yanchao Qiao |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
Respiratory rate 040301 veterinary sciences Animals Wild Injections Intramuscular 0403 veterinary science 03 medical and health sciences Immobilization 0302 clinical medicine 030202 anesthesiology biology.animal Heart rate Medicine Animals Prospective Studies Dexmedetomidine Ailuropoda melanoleuca Tiletamine General Veterinary biology medicine.diagnostic_test business.industry Atipamezole Zolazepam 04 agricultural and veterinary sciences Capillary refill Anesthetics Combined Anesthesia Female business Ursidae medicine.drug |
| Zdroj: | Veterinary anaesthesia and analgesia. 43(3) |
| ISSN: | 1467-2995 |
| Popis: | Objective To assess the effects and utility of dexmedetomidine combined with tiletamine and zolazepam (dexMTZ) to immobilize the wild giant panda. Study design Prospective clinical study. Animals Seven giant pandas ( Ailuropoda melanoleuca ), five males and two females, aged 7–20 years and weighing 69.2–132.9 kg. Methods Once an animal was located, prior data on the individual was reviewed and the panda’s previously estimated body weight was used to calculate the volumes of drugs to administer: dexmedetomidine (dexM; 8 μg kg -1 ; 0.5 mg mL -1 ) and tiletamine–zolazepam (TZ; 2 mg kg -1 ; 50 mg mL -1 ). The mixture was injected intramuscularly (IM) using the Dan-Inject pistol system. When the panda was immobilized, it was weighed, a physical examination was performed and a blood sample collected. Every 5 minutes, the heart rate (HR), respiratory rate ( f R ), rectal temperature (T), noninvasive systolic arterial pressure (SAP), capillary refill time (CRT), mucous membrane color and pulse quality were recorded. After all procedures had been completed, atipamezole (40 μg kg -1 ) was injected IM. Results A single injection of dexMTZ resulted in the immobilization of all seven giant pandas. The median (range) of anesthetic agents administered was dexM 8.4 μg kg -1 (7.3–10.5 μg kg -1 ) and TZ 2.0 mg kg -1 (1.8–2.5 mg kg -1 ). The palpebral reflex was lost 8 (7–12) minutes after the injection. Most of the physiological variables remained in the acceptable range. All procedures were completed in approximately 1 hour. Six out of the seven (85.7%) giant pandas recovered smoothly; one panda had a rough recovery. Conclusions and clinical relevance DexMTZ produced a satisfactory immobilization and a smooth recovery for wild giant pandas while allowing approximately 55 minutes for planned noninvasive procedures. |
| Databáze: | OpenAIRE |
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