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Pasichnyk S., Stakhovsky O., Gozhenko A., Pasichnyk M., Voronina O. Ultrastructural changes in renal parenchyma with renal cell carcinoma. Journal of Education, Health and Sport. 2018;8(6):446-451. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1495561 http://ojs.ukw.edu.pl/index.php/johs/article/view/6319 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part b item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author(s) 2018; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.06.2018. Revised: 12.06.2018. Accepted: 29.06.2018. Ultrastructural changes in renal parenchyma with renal cell carcinoma S. Pasichnyk1, O. Stakhovsky2, A. Gozhenko3, M. Pasichnyk1, O. Voronina4 1Lviv National Medical University named after Danylo Halytsky, Lviv, Ukraine Department of urology FPGE 2National Cancer Institute, Kiyv 3Ukrainian Research Institute of Transport Medicine of Ministry of Health of Ukraine, Odessa 4NSC Institute of Biology and Medicine, Kiyv Abstract In recent years, there has been a significant increase in incidence of the renal cell carcinoma (RCC). In the structure of cancer, this pathology is on 10th place. The surgical treatment is the most radical and most effective method of management of this disease. Currently renal resection has become a desirable alternative to radical nephrectomy for tumors of the T1 stage [6, 7, 8, 9]. Nephron-sparing interventions, compared to radical nephrectomy, showed an equivalent cancer outcome in tumors < 4 cm in diameter [1, 10]. However, there is an opinion [2] that in the intact part of the organ due to an increased functional load various pathomorphological changes may occur [3, 4 ,7]. Although, it is believed that in this cohort of patients there are no pathomorphological changes and only in rare cases, distant functional changes can be observed [5, 2]. Key words: renal cell carcinoma, nephron, nephrectomy, nephron-sparing surgery |
