A Tale of Three Gorges in the Yangtze River: Comparing the Prevalence of Metabolic Syndrome According to ATPIII, WHO, and IDF Criteria and the Association with Vascular Health in Modernizing China
| Autor: | David S. Celermajer, Yan J Hu, Yue H Yin, Kam S. Woo, An N Wei, Ruth Chan, Ping Chook |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male China Farms Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism 030204 cardiovascular system & hematology World Health Organization Cardiovascular System World health Vascular health Diagnostic Techniques Endocrine 03 medical and health sciences 0302 clinical medicine Endocrinology Rivers Environmental health Internal Medicine medicine Diabetes Mellitus Prevalence Humans Occupations Social Change Societies Medical Three gorges Aged Metabolic Syndrome business.industry Urbanization Agriculture Middle Aged medicine.disease Cross-Sectional Studies Cardiovascular Diseases Case-Control Studies Yangtze river Female Metabolic syndrome business |
| Zdroj: | Metabolic syndrome and related disorders. 17(3) |
| ISSN: | 1557-8518 |
| Popis: | Metabolic syndrome (MS) is associated with atherosclerotic diseases. The prevalence of MS according to the Adult Treatment Panel III (ATPIII), World Health Organization (WHO), and International Diabetes Federation (IDF) criteria are variable but increasing in western countries and modernizing China. This study aimed to evaluate the prevalence of MS according to these three criteria, in farmers or ex-farming residents in three-gorges territories undergoing rapid lifestyle changes.We compared 95 residents (ex-farmers) in Wu Shan (WS) (28.4% men, aged 49.7 ± 9 years) resettled uphill for 3-5 years, and 87 age- and gender-matched farmers in Da Chang (DC) (27.6% men, aged 48.8 ± 10 years) before migration. MS and other traditional risk factors were assessed and carotid intima-media thickness (IMT) measured.Ninety-nine percent of WS residents were retired or adopted nonfarming jobs. Compared with DC farmers, WS ex-farmers had higher waist circumference, low density lipoprotein-cholesterol, and triglycerides (P 0.0001), but their blood pressures, HDL-cholesterol, and fasting glucose were similar. MS were identified in 43.2% (IDF), 36.8% (WHO), and 29.5% (ATPIII) respectively in WS ex-farmers, compared with 17.2%, 13.8%, and 11.5% respectively in DC farmers. Carotid IMT was significantly higher in WS ex-farmers (0.74 ± 0.16 mm) than in DC farmers (0.64 ± 0.11 mm) (P 0.0001). On multivariate regression analysis, prevalence of MS was correlated with job nature (beta = 0.425, P 0.0001). Carotid IMT was better correlated with IDF MS criteria (beta = 0.208, P = 0.021), independent of age and WS location (regression adjusted RIDF MS criteria is more sensitive, better correlates with atherosclerosis surrogate, and accordingly is more readily applicable to modernizing China. |
| Databáze: | OpenAIRE |
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