| Autor: |
Hyun Jin, Ahn, So-Ryoung, Lee, Eue-Keun, Choi, Nan Young, Bae, Hyo-Jeong, Ahn, Soonil, Kwon, Seung-Woo, Lee, Kyung-Do, Han, Seil, Oh, Gregory Y H, Lip |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Ahn, H J, Lee, S-R, Choi, E-K, Bae, N Y, Ahn, H-J, Kwon, S, Lee, S-W, Han, K-D, Oh, S & Lip, G Y H 2023, ' Increased risk of incident atrial fibrillation in young adults with mental disorders : A nationwide population-based study ', Heart Rhythm, vol. 20, no. 3, pp. 365-373 . https://doi.org/10.1016/j.hrthm.2022.12.019 |
| DOI: |
10.1016/j.hrthm.2022.12.019 |
| Popis: |
BACKGROUND: Mental disorders and cardiovascular diseases are closely related. However, a paucity of information on the risk of incident atrial fibrillation (AF) in patients with mental disorders exists.OBJECTIVE: We aimed to assess the association between mental disorders and the risk of AF, particularly in young adults.METHODS: Using the Korean National Health Insurance Database between 2009 and 2012, we identified adults aged 20-39 years without a history of AF and who have been diagnosed with mental disorders. Mental disorders were defined as having one of the following diagnoses: depression, insomnia, anxiety disorder, bipolar disorder, or schizophrenia. The primary outcome was new-onset AF during follow-up.RESULTS: A total of 6,576,582 subjects (mean age 30.9 ± 5.0 years; 3,919,339 [59.6%] men) were included. Among the total population, 10% had mental disorders. During the follow-up period, 8932 incident AF events occurred. Patients with mental disorders showed a higher AF incidence than did those without (25.4 per 100,000 person-years vs 17.7 per 100,000 person-years). After multivariable adjustment, mental disorders were associated with a significantly higher risk of AF (adjusted hazard ratio 1.526; 95% confidence interval 1.436-1.621). Patients with bipolar disorder or schizophrenia had a 2-fold higher risk of AF and those with depression, insomnia, and anxiety disorder had a 1.5- to 1.7-fold higher risk of AF than did those without mental disorders.CONCLUSION: Young adults diagnosed with mental disorders have a higher risk of incident AF. Awareness for AF in high-risk populations should thus be considered. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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