Regulation of hemodynamic parameters under conditions of systemic administration of angiotensin II and angiotensin IV to rats after carotid glomectomy
| Autor: | E. I. Pevtsova, A. I. Elfimov, O. N. Serova, V I Torshin, L. V. Shevchenko, A. V. Kotov |
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| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Hemodynamics Blood Pressure General Biochemistry Genetics and Molecular Biology Angiotensin IV Heart Rate Internal medicine medicine Animals Rats Wistar Carotid Body business.industry Angiotensin II General Medicine Carotid glomectomy Rats Vasomotor System Endocrinology medicine.anatomical_structure Cardiology Systemic administration Carotid body business |
| Zdroj: | Bulletin of experimental biology and medicine. 152(1) |
| ISSN: | 1573-8221 |
| Popis: | Systemic administration of angiotensin II was followed by an increase in systolic BP and HR in rats with carotid glomectomy, the time of attaining maximum values in treated animals was much higher than in sham-operated controls. Injection of angiotensin IV slightly reduced systolic BP in sham-operated animals and increased it in rats with carotid glomectomy. The involvement of the local renin-angiotensin system of the carotid body in systemic mechanisms of hemodynamics regulation is discussed. |
| Databáze: | OpenAIRE |
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