Glycemic Control, Hand Activity, and Complexity of Biological Signals in Diabetes Mellitus

Autor: Gen-Min Lin, Chieh-Ming Yang, Hsien-Tsai Wu, Bagus Haryadi, Hsiao-Chiang Chu
Rok vydání: 2017
Předmět:
Zdroj: Complexity, Vol 2017 (2017)
ISSN: 1099-0526
1076-2787
DOI: 10.1155/2017/3472121
Popis: Both glycemic control and handgrip strength affect microvascular function. Multiscale entropy (MSE) of photoplethysmographic (PPG) pulse amplitudes may differ by diabetes status and hand activity. Of a middle-to-old aged and right-handed cohort without clinical cardiovascular disease, we controlled age, sex, and weight to select the unaffected (no type 2 diabetes,n=36),the well-controlled diabetes (HbA1c < 8%,n=22), and the poorly controlled diabetes (HbA1c ≥ 8%,n=22) groups. MSEs were calculated from consecutive 1,500 PPG pulse amplitudes of bilateral index fingertips. Thesmall-, medium-,and large-scale MSEs were defined as the average of scale 1 (MSE1), scales 2–4 (MSE2–4), and scales 5–10 (MSE5–10), respectively. Intra- and intergroups were compared by one- and two-samplet-tests, respectively. The dominant handMSE5–10was lower in the poorly controlled diabetes group than the well-controlled diabetes and the unaffected (1.28 versus 1.52 and 1.56,p=0.019and 0.001, resp.) groups, whereas the nondominant handMSE5–10was lower in the well- and poorly controlled diabetes groups than the unaffected group (1.35 and 1.29 versus 1.58,p=0.008and 0.005, resp.). TheMSE1of dominant hand was higher than that of nondominant hand in the well-controlled diabetes (1.35 versus 1.10,p=0.048). In conclusion, diabetes status and hand dominance may affect the MSE of PPG pulse amplitudes.
Databáze: OpenAIRE
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