E-cigarette exposure with or without heating the e-liquid induces differential remodeling in the lungs and right heart of mice

Autor:	Yohannes, Getiye, Matthew R, Peterson, Brandon D, Phillips, Daniel, Carrillo, Bledar, Bisha, Guanglong, He
Rok vydání:	2022
Předmět:	CARD Signaling Adaptor Proteins Heating Mice Inbred C57BL Mice Inflammasomes NLR Family Pyrin Domain-Containing 3 Protein Animals Electronic Nicotine Delivery Systems Cardiology and Cardiovascular Medicine Lung Molecular Biology
Zdroj:	Journal of Molecular and Cellular Cardiology. 168:83-95
ISSN:	0022-2828
Popis:	Various cardiopulmonary pathologies associated with electronic cigarette (EC) vaping have been reported. This study investigated the differential adverse effects of heating-associated by-products versus the intact components of EC aerosol to the lungs and heart of mice. We further dissected the roles of caspase recruitment domain-containing protein 9 (CARD9)-associated innate immune response and NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome in EC exposure-induced cardiopulmonary injury. C57BL/6 wild type (WT), CARD9
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1593c0d732de2be1a546d76611239cce https://doi.org/10.1016/j.yjmcc.2022.04.014 Zobrazit plný text záznamu Full Text from ScienceDirect