Biopsy Grade Group as a reliable prognostic factor for BCR in Afro-Caribbean men with intermediate- and high-risk prostate cancer
| Autor: | Laurent Brureau, V. Roux, G. Gourtaud, Pascal Blanchet, Remi Eyraud, Clément Moureaux, Sofiane Seddik, Emmanuel Perrot |
|---|---|
| Přispěvatelé: | CHU Pointe-à-Pitre/Abymes [Guadeloupe], Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École des Hautes Études en Santé Publique [EHESP] (EHESP), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Biochemical recurrence
Adult Male medicine.medical_specialty Multivariate analysis Urology Biopsy [SDV]Life Sciences [q-bio] Population 030232 urology & nephrology Grade Group Black People Gastroenterology Risk Assessment ISUP classification Disease-Free Survival 03 medical and health sciences Prostate cancer 0302 clinical medicine Internal medicine Medicine Humans Stage (cooking) 10. No inequality education Survival analysis Aged Retrospective Studies education.field_of_study business.industry Proportional hazards model Prostatic Neoplasms Retrospective cohort study Middle Aged medicine.disease Prognosis Survival Analysis 3. Good health Caribbean Region 030220 oncology & carcinogenesis Neoplasm Grading business Afro-Caribbean |
| Zdroj: | World Journal of Urology World Journal of Urology, Springer Verlag, 2020, 38 (6), pp.1493-1499. ⟨10.1007/s00345-019-02931-3⟩ World Journal of Urology, 2020, 38 (6), pp.1493-1499. ⟨10.1007/s00345-019-02931-3⟩ |
| ISSN: | 0724-4983 1433-8726 |
| Popis: | International audience; Purpose - The Grade Group (GG) classification is recommended by guidelines as a reliable prognostic factor of prostate cancer. However, most studies have been performed on the Caucasian population. Our objective was to validate GG classification as a safe way to classify intermediate- and high-risk patients with African ancestry. Patients and methods - This was a retrospective study in an Afro-Caribbean population. A total of 1236 patients were included between 2000 and 2015. Patients were stratified according to (GG). Survival analysis was performed using the Kaplan-Meier method, univariate and multivariate analyses using the Cox model. Results - There was no significant difference at 5 and 10-year BCR-free survival between the intermediate- and high-risk groups, based on the D'Amico classification. There was a highly significant difference in BCR-free survival at 5 (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink