Sex-specific associations of birth weight with measures of adiposity in mid-to-late adulthood: the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

Autor: Vivian Cristine Luft, Lawrence J. Appel, Maria Inês Schmidt, Noel T. Mueller, Bruce Bartholow Duncan, G Rockenbach, I. M. Bensenor, Sheila Maria Alvim Matos, Sandhi Maria Barreto, Maria de Jesus Mendes da Fonseca, Álvaro Vigo, M C Stein
Rok vydání: 2016
Předmět:
Zdroj: International Journal of Obesity. 40:1286-1291
ISSN: 1476-5497
0307-0565
DOI: 10.1038/ijo.2016.76
Popis: BACKGROUND/OBJECTIVES: To investigate sex-specific associations of birth weight with body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) in mid-to-late adulthood. SUBJECTS/METHODS: ELSA-Brasil is a multicenter cohort study of adults aged 35–74 years affiliated with universities or research institutions of six capital cities in Brazil. After exclusions, we investigated 11 636 participants. Socio-demographic factors and birth weight were obtained by interview. All anthropometry was directly measured at baseline. We categorized birth weight as low (⩽2.5 kg); normal (2.5–4 kg) and high (⩾4 kg). We performed analysis of covariance (ANCOVA) for continuous outcomes and ordinal logistic regression for categorical adiposity outcomes. We examined interaction on the multiplicative scale by sex and by race. RESULTS: High birth weight uniformly predicted greater overall and central obesity in men and women. However, low (vs normal) birth weight, in ANCOVA models adjusted for participant age, family income, race, education, maternal education, and maternal and paternal history of diabetes, was associated with lower BMI, WC and WHR means for men, but not for women (P(interaction) = 0.01
Databáze: OpenAIRE