Acral Necrotizing Mycosis Fungoides
| Autor: | Dan Jones, Tasneem Poonawalla, Fredrick B. Hagemeister, Madeleine Duvic |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Male
Epstein-Barr Virus Infections Cancer Research Pathology medicine.medical_specialty Skin Neoplasms Hypogammaglobulinemia Necrosis Mycosis Fungoides medicine Humans Veillonella species Capnocytophaga species Aged Mycosis fungoides business.industry Cutaneous T-cell lymphoma Candidiasis Bacterial Infections Hematology General Medicine Gene rearrangement medicine.disease Dermatology Lymphoma Oncology Lip Neoplasms business |
| Zdroj: | Clinical Lymphoma and Myeloma. 6:146-148 |
| ISSN: | 1557-9190 |
| Popis: | A 65-year-old male with long-standing acral "eczema" and patches of mycosis fungoides suddenly developed a transformed, necrotizing ulcerative cutaneous T-cell lymphoma manifesting as necrotic lesions of the toe and lip. The tumor had brown and/or black eschars on the surface and grew multiple opportunistic organisms. Markers CD3, Epstein-Barr virus–encoded small RNA, and T-cell receptor γ gene rearrangement were positive, with CD4, 8, 30, 56, and TIA-1 negative. In spite of initial response to radiation, the patient succumbed to infection within 3 months. |
| Databáze: | OpenAIRE |
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