Perceived Significance of Isolated HBcAb in Patients with HIV: A Survey of Practitioners

Autor: Neena Thomas-Gosain, Oluwatoyin Adeyemi
Rok vydání: 2007
Předmět:
Zdroj: AIDS Patient Care and STDs. 21:385-389
ISSN: 1557-7449
1087-2914
DOI: 10.1089/apc.2006.0083
Popis: The prevalence of the isolated hepatitis B core Ab phenotype (hepatitis B surface antigen negative [HBsAg-] hepatitis B surface antibody negative [HBsAb-], and hepatitis B core antibody positive [HBcAb+] is particularly high among human HIV-positive patients. Controversy exists regarding both the significance of this phenotype and the risk of progressive liver disease as well as the need for hepatitis B vaccination in this population. A survey of 40 HIV primary care providers (PCPs) at an urban outpatient HIV clinic was conducted in 2005 regarding these two issues and a summary of the findings are presented in this report. Seventy-eight percent thought that these patients' infection had resolved and were immune, half thought they were at risk for progressive liver disease, and 6 (15%) routinely administered hepatitis B vaccine to patients with this phenotype. The wide variety in attitudes and practices among providers in a single clinic suggests the need for further research and development of management guidelines in this group of patients.
Databáze: OpenAIRE