Perceived Significance of Isolated HBcAb in Patients with HIV: A Survey of Practitioners
Autor: | Neena Thomas-Gosain, Oluwatoyin Adeyemi |
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Rok vydání: | 2007 |
Předmět: |
Hepatitis B surface antigen negative
Hepatitis B Surface Antigens business.industry Public Health Environmental and Occupational Health Human immunodeficiency virus (HIV) Physicians Family HIV Infections Hepatitis B medicine.disease_cause Hepatitis B Core Antigens Virology Infectious Diseases Risk Factors Surveys and Questionnaires Immunology Hepatitis B surface antibody medicine Humans HEPATITIS B CORE ANTIBODY POSITIVE Hepatitis B Vaccines In patient Hepatitis B Antibodies business Hepatitis b core |
Zdroj: | AIDS Patient Care and STDs. 21:385-389 |
ISSN: | 1557-7449 1087-2914 |
DOI: | 10.1089/apc.2006.0083 |
Popis: | The prevalence of the isolated hepatitis B core Ab phenotype (hepatitis B surface antigen negative [HBsAg-] hepatitis B surface antibody negative [HBsAb-], and hepatitis B core antibody positive [HBcAb+] is particularly high among human HIV-positive patients. Controversy exists regarding both the significance of this phenotype and the risk of progressive liver disease as well as the need for hepatitis B vaccination in this population. A survey of 40 HIV primary care providers (PCPs) at an urban outpatient HIV clinic was conducted in 2005 regarding these two issues and a summary of the findings are presented in this report. Seventy-eight percent thought that these patients' infection had resolved and were immune, half thought they were at risk for progressive liver disease, and 6 (15%) routinely administered hepatitis B vaccine to patients with this phenotype. The wide variety in attitudes and practices among providers in a single clinic suggests the need for further research and development of management guidelines in this group of patients. |
Databáze: | OpenAIRE |
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