The Priority Toxicant Reference Range Study: Interim Report
| Autor: | James L. Pirkle, Larry L. Needham, Eric J. Sampson, David L. Ashley, Robert H. Hill |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Adult
medicine.medical_specialty Health Toxicology and Mutagenesis education National Center for Health Statistics U.S Reference range Hazardous Substances Specimen Handling chemistry.chemical_compound Reference Values Environmental health medicine Humans natural sciences Research article Pesticides Interim report health care economics and organizations Public health Public Health Environmental and Occupational Health Middle Aged United States humanities body regions chemistry Human exposure Reference values Environmental science Research Article Toxicant |
| Zdroj: | Environmental Health Perspectives |
| ISSN: | 0091-6765 |
| Popis: | The relationship between human exposure to environmental toxicants and health effects is of utmost interest to public health scientists. To define this relationship, these scientists need accurate and precise methods for assessing human exposure and effects. One of the most accurate and precise means of assessing exposure is to measure the level of the toxicant or its primary metabolite in a biologic specimen; this has been defined as measuring the internal dose. This measurement must be quantitative to best study the dose-response relationship. Pertinent questions asked during an exposure assessment include "How do the levels of a given toxicant in a particular population compare with the levels of that toxicant in other populations?" and "What is the prevalence of exposure to that toxicant in other populations?" To answer these questions for two chemical classes of environmental toxicants, we developed state-of-the-art analytic methods and then applied them to measure the levels of 44 environmental toxicants in biologic specimens from 1000 United States residents who participated in the Third National Health and Nutrition Examination Survey (NHANES III). These 1000 people are a cross-sectional subset of the NHANES III population and were selected from urban and rural communities in four regions of the United States; all were between 20 and 59 years of age. This subset is not a probability-based sample.(ABSTRACT TRUNCATED AT 250 WORDS) |
| Databáze: | OpenAIRE |
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