Role of cow urine on the onset of leptazole-induced convulsion in Wistar rats

Autor: D Atsukwei, SA Seriki, Alexander B. Adelaiye
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Pharmacy & Bioresources; Vol 11, No 2 (2014); 34-38
ISSN: 0189-8442
Popis: The study investigated the possible preventive role of cow urine on the onset of pentylenetetrazole (leptazole) induced convulsion in Wistar rats. Forty rats (each weighing 100-120g) in four groups were used. Two groups were orally administered with varying doses of cow urine and, after 60 minutes, convulsive dose (0.2ml/kg) of leptazole, administered intraperitoneally. A reference group, not given cow urine, was given same dose of leptazole only, and another group, which was given neither cow urine nor leptazole, served as control. Results showed that cow urine did not prevent convulsion as there was no significant difference (P
Databáze: OpenAIRE