Impaired modulation of quadriceps tendon jerk reflex during spastic gait: differences between spinal and cerebral lesions
| Autor: | Wiltrud Berger, Volker Dietz, M. Faist, Matthias Ertel |
|---|---|
| Přispěvatelé: | University of Zurich, Faist, Michael |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Crossed extensor reflex Spastic gait medicine.medical_specialty Adolescent Triceps reflex Hemiplegia 610 Medicine & health 142-005 142-005 050105 experimental psychology Functional Laterality 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation Moro reflex Reflex medicine Humans 0501 psychology and cognitive sciences Spasticity 10. No inequality Muscle Skeletal Gait Spinal Cord Injuries Aged business.industry Electromyography 05 social sciences Anatomy Cerebral Infarction Middle Aged medicine.disease Ankle jerk reflex Paresis 2728 Neurology (clinical) Muscle Spasticity 570 Life sciences biology Female Neurology (clinical) medicine.symptom business 030217 neurology & neurosurgery Jaw jerk reflex |
| Popis: | In healthy subjects, functionally appropriate modulation of short latency leg muscle reflexes occurs during gait. This modulation has been ascribed, in part, to changes in presynaptic inhibition of Ia afferents. The changes in modulation of quadriceps tendon jerk reflexes during gait of healthy subjects were compared with those of hemi- or paraparetic spastic patients. The spasticity was due to unilateral cerebral infarction or traumatic spinal cord injury, respectively. The modulation of the quadriceps femoris tendon jerk reflex at 16 phases of the step cycle was studied. The reflex responses obtained during treadmill walking were compared with control values obtained during gait-mimicking standing postures with corresponding levels of voluntary muscle contraction and knee angles. In healthy subjects the size of the reflexes was profoundly modulated and was generally depressed throughout the step cycle. In patients with spinal lesion the reflex depression during gait was almost removed and was associated with weak or no modulation during the step cycle. In patients with cerebral lesion there was less depression of the reflex size associated with a reduced reflex modulation on the affected side compared with healthy subjects. On the `unaffected' side of these patients reflex modulation was similar to that of healthy subjects, but the reflex size during gait was not significantly different from standing control values. These observations suggest that the mechanisms responsible for the depression of reflex size and the modulation normally seen during gait in healthy subjects are impaired to different extents in spasticity of spinal or cerebral origin, possibly due to the unilateral preservation of fibre tracts in hemiparesis. |
| Databáze: | OpenAIRE |
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