Clinical validation of Endofaster� for a rapid diagnosis of Helicobacter pylori infection
| Autor: | Eugenia Sánchez Rodríguez, Enrique Vazquez-Sequeiros, Ana García García de Paredes, Rosa María Martín Mateos, Agustín Albillos, Rubén Sánchez Aldehuelo, Alejandra Caminoa, Raquel Ríos León, Carlos Martín de Argila |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Helicobacter pylori infection Adolescent Sensitivity and Specificity Gastroenterology Helicobacter Infections Young Adult 03 medical and health sciences 0302 clinical medicine Ammonia Internal medicine Biopsy medicine Humans Urea Prospective Studies Aged Bacteriological Techniques Gastric Juice Kappa value Helicobacter pylori biology medicine.diagnostic_test business.industry Area under the curve Histology General Medicine Gold standard (test) Hydrogen-Ion Concentration Middle Aged biology.organism_classification Upper gastrointestinal endoscopy Diagnostic Techniques Digestive System Area Under Curve 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology business |
| Zdroj: | Revista Española de Enfermedades Digestivas. 112 |
| ISSN: | 1130-0108 |
| Popis: | BACKGROUND this study aimed to evaluate the diagnostic accuracy of the Endofaster® for the detection of Helicobacter pylori. METHODS during upper gastrointestinal endoscopy, gastric juice was aspirated to perform an analysis using the Endofaster®. This test was considered as positive when the ammonium concentration was > 67 ppm, negative when < 57 ppm and weakly positive between 57 and 67. Biopsy specimens were also taken as the gold standard. RESULTS among the 86 patients enrolled in the study, the Endofaster® result was positive in 23.7%, negative in 54.7% and weakly positive in 11.6%, whereas infection was detected via histology in 38.4% of patients. The accuracy was 81.4%, with a Kappa value of 0.57. CONCLUSIONS the Endofaster® could be useful to perform a rapid diagnosis of Helicobacter pylori infection (area under the curve = 0.81). |
| Databáze: | OpenAIRE |
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