Hypersensitivity Pneumonitis Caused by Trichoderma viride
Autor: | Alicia Enríquez-Matas, Noelia Cubero, Joaquín Sastre, Rosario Melchor, Santiago Quirce |
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Rok vydání: | 2009 |
Předmět: |
Pathology
medicine.medical_specialty Chest pain Gastroenterology Immunoglobulin G Internal medicine medicine Humans Air Conditioning Leukocytosis Antibodies Fungal Trichoderma biology medicine.diagnostic_test business.industry Trichoderma viride Oxygen Inhalation Therapy General Medicine Middle Aged medicine.disease biology.organism_classification Combined Modality Therapy Respiration Artificial Neutrophilia Anti-Bacterial Agents Bronchodilator Agents Dyspnea biology.protein Equipment Contamination Female Emergencies medicine.symptom Antibody Water Microbiology business Chest radiograph Hypersensitivity pneumonitis Alveolitis Extrinsic Allergic |
Zdroj: | Archivos de Bronconeumología ((English Edition)). 45:304-305 |
ISSN: | 1579-2129 |
DOI: | 10.1016/s1579-2129(09)72422-x |
Popis: | Hypersensitivity pneumonitis (HP) can be induced by exposure to indoor molds contaminating humidifiers and heating or ventilation systems. A 54-year-old woman with dyspnea, cough, chest pain, and fever was seen in the emergency room. A chest radiograph revealed interstitial infiltrates and blood tests showed leukocytosis with neutrophilia and severe hypoxemia. A diagnosis of HP was made by a combination of clinical, radiologic, physiologic, and immunologic studies. Trichoderma viride was isolated in cultures of water samples from an ultrasonic humidifier installed in the patient's home a year earlier. Precipitating immunoglobulin G antibodies to T viride were detected in the patient's serum by enzyme-linked immunosorbent assay. The patient remained symptom free after the humidifier was removed from her home. Our findings strongly suggest that the patient developed HP due to T viride from the humidifier. To our knowledge, this is the first report of such a case. |
Databáze: | OpenAIRE |
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