Stability Analysis and Clinic Phenomenon Simulation of a Fractional-Order HBV Infection Model
| Autor: | Shurui Song, Yongmei Su, Sinuo Liu, Xiaoke Li, Yongan Ye |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Equilibrium point
Multidisciplinary General Computer Science Logarithm Article Subject 02 engineering and technology QA75.5-76.95 01 natural sciences Stability (probability) 010101 applied mathematics Correlation HBeAg Electronic computers. Computer science 0202 electrical engineering electronic engineering information engineering Order (group theory) Applied mathematics 020201 artificial intelligence & image processing 0101 mathematics Basic reproduction number Mathematics |
| Zdroj: | Complexity, Vol 2020 (2020) |
| ISSN: | 1076-2787 |
| DOI: | 10.1155/2020/8864403 |
| Popis: | In this paper, a fractional-order HBV model was set up based on standard mass action incidences and quasisteady assumption. The basic reproductive number R0 and the cytotoxic T lymphocytes’ immune-response reproductive number R1 were derived. There were three equilibrium points of the model, and stable analysis of each equilibrium point was given with corresponding hypothesis about R0 or R1. Some numerical simulations were also given based on HBeAg clinical data, and the simulation showed that there existed positive logarithmic correlation between the number of infected cells and HBeAg, which was consistent with the clinical facts. The simulation also showed that the clinical individual differences should be reflected by the fractional-order model. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text