Use of Catridecacog in a patient with severe Factor XIII deficiency undergoing surgery
| Autor: | Francesca Luise, Gianluca Sottilotta, Alessandra Di Lelio, Vincenzo Oriana, Rosa Santacroce, Angela Piromalli |
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| Rok vydání: | 2018 |
| Předmět: |
0106 biological sciences
medicine.medical_specialty Antihemorrhagic Case Report 01 natural sciences surgery 03 medical and health sciences 0302 clinical medicine 010608 biotechnology Medicine Factor XIII deficiency In patient lcsh:RC633-647.5 business.industry congenital FXIII deficiency lcsh:Diseases of the blood and blood-forming organs Hematology Surgical procedures Factor XIII medicine.disease Recombinant FXIII Surgery Catridecacog Right inguinal hernia business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Hematology Reports Hematology Reports, Vol 11, Iss 1 (2019) |
| ISSN: | 2038-8322 |
| Popis: | Despite many articles regarding the antihemorrhagic treatment and prophylaxis, there is a lack of experience about how to best conduct major surgical procedures in patients with congenital factor XIII (FXIII) deficiency. Here we report a case of surgery (right inguinal hernia, complicated by heaviness and pain) performed in a patient with FXIII deficiency, receiving recombinant FXIII prophylaxis (Catridecacog 35 UI/kg every 28 ± 2 days). Our experience shows that Catridecacog can be used safely and effectively not only for continued prophylaxis but also in surgery and adds to the very limited body of evidence currently available on surgery in this bleeding disorder. |
| Databáze: | OpenAIRE |
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