Chest CT Diagnosis of COVID-19: Accuracy using CO-RADS and CTInvolvement Scoring
| Autor: | Brecht Van Berkel, G Verswijvel, Jan Verduyckt, M Grieten, Jan Vandevenne, Kristof Coursier, Wim Siemons, Jan Van Offenwert, Vincent Alberts |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19) rt-pcr Chest ct R895-920 Diagnostic accuracy chest Disease course Medical physics. Medical radiology. Nuclear medicine Medicine Radiology Nuclear Medicine and imaging CO- RADS Computer. Automation co-rads business.industry Retrospective cohort study Predictive value infection COVID-19 CT RT-PCR CO-RADS Chest Infection covid-19 Clinical diagnosis Thoracic imaging Original Article Human medicine Nuclear medicine business ct |
| Zdroj: | Journal of the Belgian Society of Radiology, Vol 105, Iss 1 (2021) Journal of the Belgian Society of Radiology Journal of the Belgian Society of Radiology; Vol 105, No 1 (2021); 17 |
| ISSN: | 2514-8281 |
| Popis: | Objectives: Both Reporting and Data System (CO-RADS) and CT-involvement scores (CTIS) have been proposed for evaluation of COVID-19 on chest CT. The purpose of this single-center, retrospective study was to evaluate both scoring systems to diagnose COVID-19 infection in a high-prevalence area. Materials and Methods: Chest CT datasets (n = 200) and available reverse transcription polymerase chain reaction (RT-PCR) on nasopharyngeal swab were included. CT scans were assigned to four 'imaging groups' after scoring for both CO-RADS and CTIS. Diagnostic accuracy of chest CT was calculated respectively using RT-PCR and clinical diagnosis as gold standards: False-negatives and false-positives of chest CT regarding RT-PCR were studied in more depth using the medical files. Results: The 'imaging group' including CO-RADS 4/5 scores reached the highest diagnostic values for COVID-19 considering either the initial RT-PCR or the final clinical diagnosis as the standard of reference: accuracies of 172/200 (86%) to 181/200 (90.5%), sensitivities of 60/80 (88.2%) to 70/79 (88.6%), specificities of 112/132 (84.9%) to 111/121 (91.7%), negative predictive values (NPV) of 112/120 (93.3%) to 111/120 (92.5%), respectively. False-negative CTs regarding RT-PCR were mainly explained by imaging very early in the disease course (5 out of 8 cases) or COVID-19 infection with no/minor respiratory symptoms (3 out of 8 cases). Conclusion: Assessing chest CT using CO-RADS is a valuable diagnostic approach for COVID-19 infection in a high-prevalence area, with a higher accuracy than CTIS. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|