Health-related quality of life in oropharyngeal cancer survivors – a population-based study
| Autor: | Thomas Wilhelm, S Singer, Thomas Guenzel, M Eichler, M Schimmer, U Walliczek-Dworschak, Afshin Teymoortash, Achim M. Franzen |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty medicine.medical_treatment 03 medical and health sciences 0302 clinical medicine Cancer Survivors Swallowing Quality of life Surveys and Questionnaires Internal medicine medicine Humans Definitive radiotherapy Aged Aged 80 and over Health related quality of life business.industry Cancer Middle Aged medicine.disease humanities Confidence interval Population based study Oropharyngeal Neoplasms 030104 developmental biology Otorhinolaryngology 030220 oncology & carcinogenesis Quality of Life Female business Adjuvant |
| Zdroj: | Otolaryngologia Polska. 72:30-35 |
| ISSN: | 2300-8423 0030-6657 |
| Popis: | Objective: The aim of this study was to compare QoL of oropharyngeal cancer survivors who had received different treatments. Subjects and methods: We contacted 954 survivors. Each survivor received the QoL questionnaires EORTC QLQ-C30 and EORTC QLQ-H&N35. Results: A total of 263 survivors completed the questionnaires (28% responses). Forty-five of them had undergone surgery, 20 had received definitive radiotherapy or chemo-radiotherapy, 85 surgery plus adjuvant radiotherapy, and 111 surgery plus adjuvant chemo-radiotherapy. Survivors who had received adjuvant radiotherapy and surgery reported significantly more problems with swallowing (B=13.43 [95% Confidence Interval (CI) 1.83-25.03]), senses (B=24,91 [CI 11.86-37.97]), eating (B=16.91 [CI 3.46-30.36]), dry mouth (B=26.42 [CI 12.17-40.67]), sticky saliva (B=22.37 [CI 6.23-38.50]) and nutritional supplements (B=18.59 [CI 0.62-36.56]) than those who had received surgery only. Survivors who had received adjuvant chemo-radiotherapy and surgery reported significantly many more problems with dry mouth (B=34.15 [CI 18.91-49.39]) and sticky saliva (B=22.90 [CI 5.65-40.16]), and fewer problems with physical functioning (B=-12.07 [CI 0.49-23-64]). Conclusion: Survivors who participated in this survey and who had undergone surgery alone reported in some head- and neck-specific domains a better health-related quality of life than patients who had undergone multi-modal treatment or adjuvant radiotherapy. |
| Databáze: | OpenAIRE |
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