Polyglucosan bodies in sural nerve biopsies
| Autor: | M. A. van 't Hof, H. L. S. M. Busard, Fons J. M. Gabreëls, A. A. W. M. Gabreëls-Festen, W. O. Renier |
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| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Adolescent Biopsy Central nervous system Sural nerve Pathology and Forensic Medicine Cellular and Molecular Neuroscience Degenerative disease Sural Nerve medicine Humans Child Glucans Aged Retrospective Studies Aged 80 and over medicine.diagnostic_test business.industry Age Factors Adult polyglucosan body disease Middle Aged medicine.disease medicine.anatomical_structure Lafora's disease Child Preschool Female Neurology (clinical) Nervous System Diseases medicine.symptom business Myoclonus Polyneuropathy |
| Zdroj: | Acta Neuropathologica. 80:554-557 |
| ISSN: | 1432-0533 0001-6322 |
| DOI: | 10.1007/bf00294618 |
| Popis: | The presence of polyglucosan bodies in sural nerves collected over a 16-year period was studied in relation to age, sex, presence of polyneuropathy, and concomitant presence of central nervous system disorder. Polyglucosan bodies have been seen in only one patient without a polyneuropathy. This patient was suffering from Lafora's disease. In all other sural nerves positive for polyglucosan bodies a polyneuropathy was present. Within this group the prevalence of polyglucosan bodies was positively correlated with age, and if a central nervous system disorder was associated, this prevalence was more distinct. With semiquantitative measurements of the surface of polyglucosan bodies a significant correlation was found between age and percentage of large bodies. |
| Databáze: | OpenAIRE |
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