PEDRo: A database for storing, searching and disseminating experimental proteomics data

Autor: Simon J. Gaskell, Zhikang Yin, Kathleen M. Carroll, Julie Howard, Keith F. Chater, Chris F. Taylor, Sarah R. Hart, Alistair J. P. Brown, Caroline A. Evans, Norman Morrison, Lena Hansson, Norman W. Paton, Stephen G. Oliver, David Stead, Kathryn S. Lilley, Andy Brass, Muriel Mewissen, Thomas McLaughlin, Peter Ghazal, Kevin Garwood, Andrew Hesketh, Anthony D. Whetton, Chris Garwood, Scott Joens, Simon J. Hubbard
Přispěvatelé: Lilley, Kathryn [0000-0003-0594-6543], Oliver, Stephen [0000-0001-6330-7526], Apollo - University of Cambridge Repository
Rok vydání: 2004
Předmět:
Proteomics
Saccharomyces cerevisiae Proteins
lcsh:QH426-470
GeneralLiterature_INTRODUCTORYANDSURVEY
lcsh:Biotechnology
Data management
Candida glabrata
Streptomyces coelicolor
Biology
computer.software_genre
Database
Fungal Proteins
Mice
03 medical and health sciences
Upload
0302 clinical medicine
Bacterial Proteins
Software Design
lcsh:TP248.13-248.65
Candida albicans
Genetics
Human proteome project
Animals
Databases
Protein
Trichinella spiralis
030304 developmental biology
0303 health sciences
Fungal protein
Arabidopsis Proteins
business.industry
QH
Computational Biology
Proteins
Experimental data
Trichinellosis
Helminth Proteins
Jejunal Diseases
lcsh:Genetics
ComputingMethodologies_PATTERNRECOGNITION
Data model
030220 oncology & carcinogenesis
Proteome
Database Management Systems
business
computer
Biotechnology
Zdroj: BMC Genomics, Vol 5, Iss 1, p 68 (2004)
Garwood, K, McLaughlin, T, Garwood, C, Joens, S, Morrison, N, Taylor, C F, Carroll, K, Evans, C, Whetton, A D, Hart, S, Stead, D, Yin, Z, Brown, A J P, Hesketh, A, Chater, K, Hansson, L, Mewissen, M, Ghazal, P, Howard, J, Lilley, K S, Gaskell, S J, Brass, A, Hubbard, S J, Oliver, S G & Paton, N W 2004, ' PEDRo: a database for storing, searching and disseminating experimental proteomics data ', BMC Genomics, vol. 5, pp. 68 . https://doi.org/10.1186/1471-2164-5-68
BMC Genomics
ISSN: 1471-2164
DOI: 10.1186/1471-2164-5-68
Popis: Background Proteomics is rapidly evolving into a high-throughput technology, in which substantial and systematic studies are conducted on samples from a wide range of physiological, developmental, or pathological conditions. Reference maps from 2D gels are widely circulated. However, there is, as yet, no formally accepted standard representation to support the sharing of proteomics data, and little systematic dissemination of comprehensive proteomic data sets. Results This paper describes the design, implementation and use of a Proteome Experimental Data Repository (PEDRo), which makes comprehensive proteomics data sets available for browsing, searching and downloading. It is also serves to extend the debate on the level of detail at which proteomics data should be captured, the sorts of facilities that should be provided by proteome data management systems, and the techniques by which such facilities can be made available. Conclusions The PEDRo database provides access to a collection of comprehensive descriptions of experimental data sets in proteomics. Not only are these data sets interesting in and of themselves, they also provide a useful early validation of the PEDRo data model, which has served as a starting point for the ongoing standardisation activity through the Proteome Standards Initiative of the Human Proteome Organisation.
Databáze: OpenAIRE
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