Comparison of the methods of artificial insemination on the incidence of conception in single unmarried women

Autor: Bryan R. Hecht, Rajasingam S. Jeyendran, Albert J. Peters, Anne Colston Wentz
Rok vydání: 1993
Předmět:
Zdroj: Fertility and Sterility. 59:121-124
ISSN: 0015-0282
DOI: 10.1016/s0015-0282(16)55626-x
Popis: Objective To compare pregnancy rates after intrauterine insemination (IUI) versus pericervical insemination in absolute male factor infertility using each patient as her own control. Design Ovulatory women with patent fallopian tubes without male partners were alternately inseminated with cryopreserved donor semen using either IUI or pericervical insemination techniques. A total of 81 cycles, which included up to 4 cycles per patient were performed. In this manner a comparison between the efficacy of each method could be evaluated. Setting The donor insemination program at the Center For Assisted Reproduction at Northwestern University Medical School. Patients Twenty-six single, healthy, unmarried women with patent fallopian tubes and Main Outcome Measures Positive quantitative serum subunit of human chorionic gonadotropin followed by the presence of an intrauterine gestational sac seen by transvaginal ultrasonography. Results Fourteen (54%) of 26 patients conceived including two (14%) miscarriages within four insemination cycles. Seven (17.5%) patients after IUI, and 7 (17.1%) patients after pericervical insemination conceived. The pregnancy rates were similar regardless of the order of insemination method. Conclusion These findings reveal that there is no statistical difference in the pregnancy outcome between these two methods of insemination in absolute male factor infertility.
Databáze: OpenAIRE