Biophysical properties of the neck skin indicating potential complications of salvage surgery for laryngeal/hypopharyngeal cancer

Autor:	Jun-Ichi, Ohkubo, Tetsuro, Wakasugi, Shoko, Takeuchi, Azusa, Takahashi, Thi Nga, Nguyen, Hideaki, Suzuki
Rok vydání:	2022
Předmět:	Salvage Therapy Hypopharyngeal Neoplasms Postoperative Complications Treatment Outcome Otorhinolaryngology Carcinoma Squamous Cell Humans Chemoradiotherapy General Medicine Neoplasm Recurrence Local Laryngeal Neoplasms Retrospective Studies
Zdroj:	Acta Oto-Laryngologica. 142:634-637
ISSN:	1651-2251 0001-6489
Popis:	Chemoradiation therapy is standard practice for hypopharyngeal and laryngeal cancer, but its impact on skin health can cause complications if salvage surgery is required.To develop simple objective indices for the early detection of complications following head-and-neck salvage surgery.Preoperatively and on postoperative days 1, 3, 5 and 7, we measured skin hardness (N), interstitial liquid content (П) and intracellular liquid content (W) as biophysical properties in patients who underwent post-CRT salvage therapy and those who underwent total organ resection without CRT as controls. We then analyzed these data in relation to occurrence of complications.In 11 patients undergoing salvage surgery and 23 controls, complications tended to be higher (N, П and W are useful measurements for the early identification of patients likely to develop complications.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1562b4ddb53d5941fd76ad4b3cf64dc2 https://doi.org/10.1080/00016489.2022.2117411 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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