Neurodevelopmental outcomes in congenital heart disease through the lens of single ventricle patients
| Autor: | Lindsey A McPhillips, Robin Varughese, Joseph Burns, Arushi Dhar, Madhusudan Ganigara, Sanjeev V. Kothare |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Heart Defects
Congenital medicine.medical_specialty Heart disease business.industry medicine.medical_treatment MEDLINE medicine.disease Patient population medicine.anatomical_structure Ventricle Survivorship curve Pediatrics Perinatology and Child Health medicine Humans Cognitive skill Cardiac monitoring Intensive care medicine business |
| Zdroj: | Current Opinion in Pediatrics. 33:535-542 |
| ISSN: | 1531-698X 1040-8703 |
| Popis: | Purpose of review This review aims to summarize and organize the current body of literature on this contemporary topic, alongside a more general discussion of neurodevelopmental complications of congenital heart disease. Recent findings It is theorized that the causes of the neurodevelopment disabilities are multifactorial resulting from structural central nervous system abnormalities, haemodynamic alterations and/or biochemical changes. It is therefore imperative that all patients with single ventricle anatomy and physiology receive long-term neurologic and developmental assessments in addition to their cardiac monitoring. Summary Advancements in surgical techniques and medical management have improved survivorship of these medically complex patients. Neurodevelopmental sequelae are one of the most common comorbidities affecting this patient population leading to long-term challenges in motor, language, social and cognitive skills. |
| Databáze: | OpenAIRE |
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