Immunofluorescence patterns in dermatitis herpetiformis. Investigations on skin and intestinal mucosa
| Autor: | Maja Doralt, Karl Holubar, G. Eggerth |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Biopsy Dermatitis Herpetiformis Fluorescent Antibody Technique Immunoglobulins Dermatology Immunofluorescence Intestinal mucosa Antigen Dermatitis herpetiformis medicine Humans Antigens Intestinal Mucosa Aged Autoantibodies Skin integumentary system medicine.diagnostic_test business.industry Circulating antibodies Complement System Proteins Middle Aged medicine.disease Skin symptoms Immunoglobulin A Jejunum Immunology business |
| Zdroj: | The British journal of dermatology. 85(6) |
| ISSN: | 0007-0963 |
| Popis: | Summary.— An attempt has been made to detect Ig deposits in skin and upper intestinal mucosa, and circulating antibodies in the serum, of patients with dermatitis herpetiformis. Deposits containing IgA and complement (C3’) were traced in the lesional skin of 11 of 12 patients. One patient wbo was free of skin symptoms failed to exhibit similar findings. Specimens of upper intestinal mucosa (9 patients), did not show a similar pattern of junctional IF; however a marked flattening of the mucosal relief was observed in 6 patients. Circulating antibodies against junctional antigens of skin or jejunal tissue were not demonstrated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text