Influence of Ionizing Radiation on Nucleus 24 Cochlear Implants
| Autor: | Roland Laszig, F. B. Knapp, Antje Aschendorff, H Mauch, F Röhner, Thomas Klenzner, P Pedersen, Johannes Lutterbach, E von Wallenberg |
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| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_treatment
Ionizing radiation Radiation Ionizing Cochlear implant Electric Impedance medicine Humans Telemetry Radiotherapy Phantoms Imaging business.industry Pulse (signal processing) Dose-Response Relationship Radiation Equipment Design Models Theoretical Sensory Systems Hyperfractionated radiotherapy Radiation therapy Cochlear Implants medicine.anatomical_structure Otorhinolaryngology Neurology (clinical) Implant Tomography X-Ray Computed business Nuclear medicine Nucleus Hyperfractionation |
| Zdroj: | Otology & Neurotology. 26:661-667 |
| ISSN: | 1531-7129 |
| Popis: | HYPOTHESIS To evaluate the influence of conventional or hyperfractionated radiotherapy on Nucleus CI24M or CI24R(CS) implant systems. BACKGROUND As a consequence of more than 70,000 cochlear implant recipients worldwide, the potential need for radiotherapy is an issue requiring consideration by both implantees and implantation centers. Conditions requiring radiotherapy of the head may include head, neck, or brain tumors. METHODS The study examines the effect of ionizing radiation on cochlear implant function. The implanted devices examined were the Nucleus CI24M and Nucleus CI24R(CS). In a modeled study, two implants of each type were treated with fraction schemes most frequently used in clinical routine (e.g., conventional fractionation [total dose, 120 Gy] and hyperfractionation [total dose, 116 Gy]). Parameters quantified were the implant output amplitude changes at high and low current level (current levels 255 and 100, respectively), the charge balance of the biphasic pulse, and the accuracy of the impedance telemetry function. RESULTS Within the clinically relevant dose range (< 80 Gy), implant function in all four devices was normal. Failure occurred in one Nucleus CI24R(CS) device treated with hyperfractionation. A dramatic drop in the output amplitude at 106 Gy was observed, and the impedance measurement failed at a total dose of 111 Gy. CONCLUSION The results suggest that conventional or hyperfractionated radiotherapy can be applied safely at Nucleus CI24M or CI24R(CS) implant systems in a patient-like setting. Therefore, the authors propose that the results of the study can be applicable in clinical practice. |
| Databáze: | OpenAIRE |
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